Paper

Self-Assembled Microarrays of Attoliter Molecular Vessels

Abstract

High-density microarrays of attoliter volume elements can be created (see figure) within minutes in a parallel and effortless manner by using self-assembly of nanometer-size components based on biological recognition. These ultrasmall volumes allow localization of single molecules, screening for (bio)chemical properties, and assessing the performance of confined chemical reactions.

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